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HIV-1 Suppressive Sequences Are Modulated by Rev Transport of Unspliced RNA and Are Required for Efficient HIV-1 Production

The unspliced human immunodeficiency virus type 1 (HIV-1) RNAs are translated as Gag and Gag-Pol polyproteins or packaged as genomes into viral particles. Efficient translation is necessary before the transition to produce infective virions. The viral protein Rev exports all intron-containing viral...

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Detalles Bibliográficos
Autores principales: Noguchi, Kousei, Ishibashi, Keisuke, Miyokawa, Kaori, Hokari, Manami, Kanno, Tomoyuki, Hirano, Tomoya, Yamamoto, Norio, Takaku, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519575/
https://www.ncbi.nlm.nih.gov/pubmed/23251516
http://dx.doi.org/10.1371/journal.pone.0051393