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A Novel Bipartite Nuclear Localization Signal Guides BPM1 Protein to Nucleolus Suggesting Its Cullin3 Independent Function

BPM1 belongs to the MATH-BTB family of proteins, which act as substrate-binding adaptors for the Cullin3-based E3 ubiquitin ligase. MATH-BTB proteins associate with Cullin3 via the BTB domain and with the substrate protein via the MATH domain. Few BPM1-interacting proteins with different functions a...

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Detalles Bibliográficos
Autores principales: Leljak Levanić, Dunja, Horvat, Tomislav, Martinčić, Jelena, Bauer, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519589/
https://www.ncbi.nlm.nih.gov/pubmed/23251450
http://dx.doi.org/10.1371/journal.pone.0051184