The Bioenergetic Status Relates to Dopamine Neuron Loss in Familial PD with PINK1 Mutations

Mutations in the PINK1 gene cause autosomal recessive familial Parkinson’s disease (PD). The gene encodes a mitochondrial protein kinase that plays an important role in maintaining mitochondrial function and integrity. However, the pathophysiological link between mutation-related bioenergetic defici...

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Detalles Bibliográficos
Autores principales: Hilker, Rüediger, Pilatus, Ulrich, Eggers, Carsten, Hagenah, Johann, Roggendorf, Julia, Baudrexel, Simon, Klein, Johannes C., Neumaier, Bernd, Fink, Gereon R., Steinmetz, Helmuth, Klein, Christine, Hattingen, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519591/
https://www.ncbi.nlm.nih.gov/pubmed/23251494
http://dx.doi.org/10.1371/journal.pone.0051308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519591/
https://www.ncbi.nlm.nih.gov/pubmed/23251494
http://dx.doi.org/10.1371/journal.pone.0051308

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