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Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice
BACKGROUND: Evidence suggests that dendritic cells accumulate in the lungs of COPD patients and correlate with disease severity. We investigated the importance of IL-1R1 and its ligands IL-1α and β to dendritic cell accumulation and maturation in response to cigarette smoke exposure. METHODS: Mice w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519608/ https://www.ncbi.nlm.nih.gov/pubmed/22992200 http://dx.doi.org/10.1186/1465-9921-13-81 |