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Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

BACKGROUND: Evidence suggests that dendritic cells accumulate in the lungs of COPD patients and correlate with disease severity. We investigated the importance of IL-1R1 and its ligands IL-1α and β to dendritic cell accumulation and maturation in response to cigarette smoke exposure. METHODS: Mice w...

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Detalles Bibliográficos
Autores principales:	Botelho, Fernando M, Nikota, Jake K, Bauer, Carla MT, Morissette, Mathieu C, Iwakura, Yoichiro, Kolbeck, Roland, Finch, Donna, Humbles, Alison A, Stämpfli, Martin R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519608/ https://www.ncbi.nlm.nih.gov/pubmed/22992200 http://dx.doi.org/10.1186/1465-9921-13-81

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