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A Recombinant Protein Based on Trypanosoma cruzi P21 Enhances Phagocytosis

BACKGROUND: P21 is a secreted protein expressed in all developmental stages of Trypanosoma cruzi. The aim of this study was to determine the effect of the recombinant protein based on P21 (P21-His(6)) on inflammatory macrophages during phagocytosis. FINDINGS: Our results showed that P21-His(6) acts...

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Detalles Bibliográficos
Autores principales: Rodrigues, Adele A., Clemente, Tatiana M., dos Santos, Marlus A., Machado, Fabrício C., Gomes, Rafael G. B., Moreira, Heline Hellen T., Cruz, Mário C., Brígido, Paula C., dos Santos, Paulo C. F., Martins, Flávia A., Bahia, Diana, Maricato, Juliana T., Janini, Luiz M. R., Reboredo, Eduardo H., Mortara, Renato A., da Silva, Claudio V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519637/
https://www.ncbi.nlm.nih.gov/pubmed/23251513
http://dx.doi.org/10.1371/journal.pone.0051384