Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety

BACKGROUND: The disappointing clinical failures of five topical vaginal microbicides have provided new insights into factors that impact microbicide safety and efficacy. Specifically, the greater risk for human immunodeficiency virus type 1 (HIV-1) acquisition associated with multiple uses of a nono...

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Detalles Bibliográficos
Autores principales: Lozenski, Karissa, Ownbey, Robert, Wigdahl, Brian, Kish-Catalone, Tina, Krebs, Fred C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519674/
https://www.ncbi.nlm.nih.gov/pubmed/23025553
http://dx.doi.org/10.1186/2050-6511-13-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519674/
https://www.ncbi.nlm.nih.gov/pubmed/23025553
http://dx.doi.org/10.1186/2050-6511-13-9

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