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Microarray-Assisted Pathway Analysis Identifies MT1X & NFκB as Mediators of TCRP1-Associated Resistance to Cisplatin in Oral Squamous Cell Carcinoma

We recently reported that TCRP1, a novel multidrug-resistance associated human gene, can mediate cisplatin resistance in OSCC cells. However, the molecular mechanism underlying this role of TCRP1 remained to be elucidated. In this study, by using Human Toxicology and Drug Resistance Microarray, we i...

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Detalles Bibliográficos
Autores principales: Peng, Bo, Gu, Yixue, Xiong, Yan, Zheng, Guopei, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519677/
https://www.ncbi.nlm.nih.gov/pubmed/23251525
http://dx.doi.org/10.1371/journal.pone.0051413