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Upregulation of Protein Phosphatase 2A and NR3A-Pleiotropic Effect of Simvastatin on Ischemic Stroke Rats

Ca(2+) influxes are regulated by the functional state of N-methyl-D-aspartate receptors (NMDARs). Dephosphorylation of NMDARs subunits decreases Ca(2+) influxes. NR3, a novel subunit of NMDARs, also decreases Ca(2+) influxes by forming new NMDARs with NR1 and NR2. It is meaningful to uncover whether...

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Detalles Bibliográficos
Autores principales: Zhu, Minxia, Wang, Jin, Liu, Min, Du, Dongshu, Xia, Chunmei, Shen, Linlin, Zhu, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519689/
https://www.ncbi.nlm.nih.gov/pubmed/23251573
http://dx.doi.org/10.1371/journal.pone.0051552