Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing’s Sarcoma in vitro

BACKGROUND: Ewing’s sarcoma is a malignancy characterized by a specific 11:22 chromosomal translocation which generates a novel EWS-FLI1 fusion protein functioning as an aberrant transcription factor. In the present study, we have further characterized the junction region of the EWS-FLI1 fusion prot...

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Detalles Bibliográficos
Autores principales: Jully, Babu, Vijayalakshmi, Ramshankar, Gopal, Gopisetty, Sabitha, Kesavan, Rajkumar, Thangarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519708/
https://www.ncbi.nlm.nih.gov/pubmed/23145994
http://dx.doi.org/10.1186/1471-2407-12-513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519708/
https://www.ncbi.nlm.nih.gov/pubmed/23145994
http://dx.doi.org/10.1186/1471-2407-12-513

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