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Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing’s Sarcoma in vitro

BACKGROUND: Ewing’s sarcoma is a malignancy characterized by a specific 11:22 chromosomal translocation which generates a novel EWS-FLI1 fusion protein functioning as an aberrant transcription factor. In the present study, we have further characterized the junction region of the EWS-FLI1 fusion prot...

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Detalles Bibliográficos
Autores principales:	Jully, Babu, Vijayalakshmi, Ramshankar, Gopal, Gopisetty, Sabitha, Kesavan, Rajkumar, Thangarajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519708/ https://www.ncbi.nlm.nih.gov/pubmed/23145994 http://dx.doi.org/10.1186/1471-2407-12-513

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