ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

SATB1 drives metastasis when expressed in breast tumor cells by radically reprogramming gene expression. Here, we show that SATB1 also has an oncogenic activity to transform certain non-malignant breast epithelial cell lines. We studied the non-malignant MCF10A cell line, which is used widely in the...

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Detalles Bibliográficos
Autores principales: Ordinario, Ellen, Han, Hye-Jung, Furuta, Saori, Heiser, Laura M., Jakkula, Lakshmi R., Rodier, Francis, Spellman, Paul T., Campisi, Judith, Gray, Joe W., Bissell, Mina J., Kohwi, Yoshinori, Kohwi-Shigematsu, Terumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519734/
https://www.ncbi.nlm.nih.gov/pubmed/23251624
http://dx.doi.org/10.1371/journal.pone.0051786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519734/
https://www.ncbi.nlm.nih.gov/pubmed/23251624
http://dx.doi.org/10.1371/journal.pone.0051786

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