Escherichia coli–expressed near full length HIV-1 envelope glycoprotein is a highly sensitive and specific diagnostic antigen

BACKGROUND: The Human Immunodeficiency Virus type 1 (HIV-1) envelope glycoprotein gp160, useful in detecting anti-HIV-1 antibodies, is difficult to express in heterologous hosts. The major hurdles are its signal sequence, strong hydrophobic regions and heavy glycosylation. While it has not been poss...

Descripción completa

Detalles Bibliográficos
Autores principales: Talha, Sheikh M, Nemani, Satish Kumar, Salminen, Teppo, Kumar, Sushil, Swaminathan, Sathyamangalam, Soukka, Tero, Pettersson, Kim, Khanna, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519745/
https://www.ncbi.nlm.nih.gov/pubmed/23186021
http://dx.doi.org/10.1186/1471-2334-12-325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519745/
https://www.ncbi.nlm.nih.gov/pubmed/23186021
http://dx.doi.org/10.1186/1471-2334-12-325

Ejemplares similares