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Regulated protein aggregation: stress granules and neurodegeneration

The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodegenerative diseases. RNA binding prote...

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Detalles Bibliográficos
Autor principal: Wolozin, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519755/
https://www.ncbi.nlm.nih.gov/pubmed/23164372
http://dx.doi.org/10.1186/1750-1326-7-56