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Regulated protein aggregation: stress granules and neurodegeneration
The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodegenerative diseases. RNA binding prote...
Autor principal: | Wolozin, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519755/ https://www.ncbi.nlm.nih.gov/pubmed/23164372 http://dx.doi.org/10.1186/1750-1326-7-56 |
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