Adenosine Deaminase Enhances the Immunogenicity of Human Dendritic Cells from Healthy and HIV-Infected Individuals

ADA is an enzyme implicated in purine metabolism, and is critical to ensure normal immune function. Its congenital deficit leads to severe combined immunodeficiency (SCID). ADA binding to adenosine receptors on dendritic cell surface enables T-cell costimulation through CD26 crosslinking, which enha...

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Detalles Bibliográficos
Autores principales: Casanova, Víctor, Naval-Macabuhay, Isaac, Massanella, Marta, Rodríguez-García, Marta, Blanco, Julià, Gatell, José M., García, Felipe, Gallart, Teresa, Lluis, Carme, Mallol, Josefa, Franco, Rafael, Climent, Núria, McCormick, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519778/
https://www.ncbi.nlm.nih.gov/pubmed/23240012
http://dx.doi.org/10.1371/journal.pone.0051287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519778/
https://www.ncbi.nlm.nih.gov/pubmed/23240012
http://dx.doi.org/10.1371/journal.pone.0051287

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