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Peroxiredoxin 6 promotes upregulation of the prion protein (PrP) in neuronal cells of prion-infected mice

BACKGROUND: It has been widely established that the conversion of the cellular prion protein (PrP(C)) into its abnormal isoform (PrP(Sc)) is responsible for the development of transmissible spongiform encephalopathies (TSEs). However, the knowledge of the detailed molecular mechanisms and direct fun...

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Detalles Bibliográficos
Autores principales: Wagner, Wibke, Reuter, Andreas, Hüller, Petra, Löwer, Johannes, Wessler, Silja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519792/
https://www.ncbi.nlm.nih.gov/pubmed/23210548
http://dx.doi.org/10.1186/1478-811X-10-38