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Peroxiredoxin 6 promotes upregulation of the prion protein (PrP) in neuronal cells of prion-infected mice
BACKGROUND: It has been widely established that the conversion of the cellular prion protein (PrP(C)) into its abnormal isoform (PrP(Sc)) is responsible for the development of transmissible spongiform encephalopathies (TSEs). However, the knowledge of the detailed molecular mechanisms and direct fun...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519792/ https://www.ncbi.nlm.nih.gov/pubmed/23210548 http://dx.doi.org/10.1186/1478-811X-10-38 |