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Functional Characterization of TLR4 +3725 G/C Polymorphism and Association with Protection against Overweight

Subclinical low-grade systemic inflammation has been associated with obesity, insulin resistance and metabolic syndrome (MS). Recent studies have highlighted the role of gut microbiota in these disorders. The toll-like receptor 4 (TLR4) plays a key role in the innate immune response activation. We s...

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Detalles Bibliográficos
Autores principales: Penas-Steinhardt, Alberto, Barcos, Lucía Soledad, Belforte, Fiorella Sabrina, de Sereday, Martha, Vilariño, Jorge, Gonzalez, Claudio Daniel, Martínez-Larrad, María Teresa, Tellechea, Mariana Lorena, Serrano-Ríos, Manuel, Poskus, Edgardo, Frechtel, Gustavo Daniel, Leskow, Federico Coluccio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519812/
https://www.ncbi.nlm.nih.gov/pubmed/23239997
http://dx.doi.org/10.1371/journal.pone.0050992