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Functional Characterization of TLR4 +3725 G/C Polymorphism and Association with Protection against Overweight
Subclinical low-grade systemic inflammation has been associated with obesity, insulin resistance and metabolic syndrome (MS). Recent studies have highlighted the role of gut microbiota in these disorders. The toll-like receptor 4 (TLR4) plays a key role in the innate immune response activation. We s...
Autores principales: | Penas-Steinhardt, Alberto, Barcos, Lucía Soledad, Belforte, Fiorella Sabrina, de Sereday, Martha, Vilariño, Jorge, Gonzalez, Claudio Daniel, Martínez-Larrad, María Teresa, Tellechea, Mariana Lorena, Serrano-Ríos, Manuel, Poskus, Edgardo, Frechtel, Gustavo Daniel, Leskow, Federico Coluccio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519812/ https://www.ncbi.nlm.nih.gov/pubmed/23239997 http://dx.doi.org/10.1371/journal.pone.0050992 |
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