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Adaptive trial designs: a review of barriers and opportunities

Adaptive designs allow planned modifications based on data accumulating within a study. The promise of greater flexibility and efficiency stimulates increasing interest in adaptive designs from clinical, academic, and regulatory parties. When adaptive designs are used properly, efficiencies can incl...

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Detalles Bibliográficos
Autores principales: Kairalla, John A, Coffey, Christopher S, Thomann, Mitchell A, Muller, Keith E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519822/
https://www.ncbi.nlm.nih.gov/pubmed/22917111
http://dx.doi.org/10.1186/1745-6215-13-145