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Associations of BDNF Genotype and Promoter Methylation with Acute and Long-Term Stroke Outcomes in an East Asian Cohort

BACKGROUND: Brain derived neurotrophic factor (BDNF) has been shown to play an important role in poststroke recovery. BDNF secretion is influenced by genetic and epigenetic profiles. This study aimed to investigate whether BDNF val66met polymorphism and promoter methylation status were associated wi...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Min, Stewart, Robert, Park, Man-Seok, Kang, Hee-Ju, Kim, Sung-Wan, Shin, Il-Seon, Kim, Hye-Ran, Shin, Myung-Geun, Cho, Ki-Hyun, Yoon, Jin-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519835/
https://www.ncbi.nlm.nih.gov/pubmed/23240009
http://dx.doi.org/10.1371/journal.pone.0051280