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Deletional Protein Engineering Based on Stable Fold

Diversification of protein sequence-structure space is a major concern in protein engineering. Deletion mutagenesis can generate a protein sequence-structure space different from substitution mutagenesis mediated space, but it has not been widely used in protein engineering compared to substitution...

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Detalles Bibliográficos
Autores principales: Raghunathan, Govindan, Soundrarajan, Nagasundarapandian, Sokalingam, Sriram, Yun, Hyungdon, Lee, Sun-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519881/
https://www.ncbi.nlm.nih.gov/pubmed/23240034
http://dx.doi.org/10.1371/journal.pone.0051510