Toxoplasma gondii Clonal Strains All Inhibit STAT1 Transcriptional Activity but Polymorphic Effectors Differentially Modulate IFNγ Induced Gene Expression and STAT1 Phosphorylation

Host defense against the parasite Toxoplasma gondii requires the cytokine interferon-gamma (IFNγ). However, Toxoplasma inhibits the host cell transcriptional response to IFNγ, which is thought to allow the parasite to establish a chronic infection. It is not known whether all strains of Toxoplasma b...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosowski, Emily E., Saeij, Jeroen P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519884/
https://www.ncbi.nlm.nih.gov/pubmed/23240025
http://dx.doi.org/10.1371/journal.pone.0051448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519884/
https://www.ncbi.nlm.nih.gov/pubmed/23240025
http://dx.doi.org/10.1371/journal.pone.0051448

Ejemplares similares