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Development of a Dehalogenase-Based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands

Our fundamental understanding of proteins and their biological significance has been enhanced by genetic fusion tags, as they provide a convenient method for introducing unique properties to proteins so that they can be examinedin isolation. Commonly used tags satisfy many of the requirements for ap...

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Detalles Bibliográficos
Autores principales: Encell, Lance P, Friedman Ohana, Rachel, Zimmerman, Kris, Otto, Paul, Vidugiris, Gediminas, Wood, Monika G, Los, Georgyi V, McDougall, Mark G, Zimprich, Chad, Karassina, Natasha, Learish, Randall D, Hurst, Robin, Hartnett, James, Wheeler, Sarah, Stecha, Pete, English, Jami, Zhao, Kate, Mendez, Jacqui, Benink, Hélène A, Murphy, Nancy, Daniels, Danette L, Slater, Michael R, Urh, Marjeta, Darzins, Aldis, Klaubert, Dieter H, Bulleit, Robert F, Wood, Keith V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520037/
https://www.ncbi.nlm.nih.gov/pubmed/23248739
http://dx.doi.org/10.2174/1875397301206010055