Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency

The antidiabetic drug metformin efficiently circumvents the dilemma that in reducing the tumourigenicity of stem cells, their essence, specifically their pluripotency, must also be sacrificed. Metformin prevents the occurrence or drastically reduces the size and weight of teratoma-like masses after...

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Detalles Bibliográficos
Autores principales: Vazquez-Martin, Alejandro, Cufi, Sílvia, Lopez-Bonet, Eugeni, Corominas-Faja, Bruna, Oliveras-Ferraros, Cristina, Martin-Castillo, Begoña, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520055/
https://www.ncbi.nlm.nih.gov/pubmed/23236586
http://dx.doi.org/10.1038/srep00964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520055/
https://www.ncbi.nlm.nih.gov/pubmed/23236586
http://dx.doi.org/10.1038/srep00964

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