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Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis

BACKGROUND: Recent data have suggested a relationship between acute arthritic pain and acid sensing ion channel 3 (ASIC3) on primary afferent fibers innervating joints. The purpose of this study was to clarify the role of ASIC3 in a rat model of osteoarthritis (OA) which is considered a degenerative...

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Detalles Bibliográficos
Autores principales: Izumi, Masashi, Ikeuchi, Masahiko, Ji, Qinghui, Tani, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520115/
https://www.ncbi.nlm.nih.gov/pubmed/22909215
http://dx.doi.org/10.1186/1423-0127-19-77