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Flavonoid Myricetin Modulates G A B A (A) Receptor Activity through Activation of Ca (2+) Channels and CaMK-II Pathway

The flavonoid myricetin is found in several sedative herbs, for example, the St. John's Wort, but its influence on sedation and its possible mechanism of action are unknown. Using patch-clamp technique on a brain slice preparation, the present study found that myricetin promoted GABAergic activ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao Hu, Ma, Ze Gang, Rowlands, Dewi Kenneth, Gou, Yu Lin, Fok, Kin Lam, Wong, Hau Yan, Yu, Mei Kuen, Tsang, Lai Ling, Mu, Li, Chen, Lei, Yung, Wing Ho, Chung, Yiu Wa, Zhang, Bei Lin, Zhao, Hua, Chan, Hsiao Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520426/
https://www.ncbi.nlm.nih.gov/pubmed/23258999
http://dx.doi.org/10.1155/2012/758097