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Flavonoid Myricetin Modulates G A B A (A) Receptor Activity through Activation of Ca (2+) Channels and CaMK-II Pathway
The flavonoid myricetin is found in several sedative herbs, for example, the St. John's Wort, but its influence on sedation and its possible mechanism of action are unknown. Using patch-clamp technique on a brain slice preparation, the present study found that myricetin promoted GABAergic activ...
Autores principales: | Zhang, Xiao Hu, Ma, Ze Gang, Rowlands, Dewi Kenneth, Gou, Yu Lin, Fok, Kin Lam, Wong, Hau Yan, Yu, Mei Kuen, Tsang, Lai Ling, Mu, Li, Chen, Lei, Yung, Wing Ho, Chung, Yiu Wa, Zhang, Bei Lin, Zhao, Hua, Chan, Hsiao Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520426/ https://www.ncbi.nlm.nih.gov/pubmed/23258999 http://dx.doi.org/10.1155/2012/758097 |
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