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Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices

BACKGROUND: The behaviour of tumour cells depends on factors such as genetics and the tumour microenvironment. The latter plays a crucial role in normal mammary gland development and also in breast cancer initiation and progression. Breast cancer tissues tend to be highly desmoplastic and dense matr...

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Detalles Bibliográficos
Autores principales: Raviraj, Vanisri, Fok, Sandra, Zhao, Jifei, Chien, Hsin-Ya, Lyons, J Guy, Thompson, Erik W, Soon, Lilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520698/
https://www.ncbi.nlm.nih.gov/pubmed/22583596
http://dx.doi.org/10.1186/1471-2121-13-12