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Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices
BACKGROUND: The behaviour of tumour cells depends on factors such as genetics and the tumour microenvironment. The latter plays a crucial role in normal mammary gland development and also in breast cancer initiation and progression. Breast cancer tissues tend to be highly desmoplastic and dense matr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520698/ https://www.ncbi.nlm.nih.gov/pubmed/22583596 http://dx.doi.org/10.1186/1471-2121-13-12 |