Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes

BACKGROUND: Polyoxins are potent inhibitors of chitin synthetases in fungi and insects. The gene cluster responsible for biosynthesis of polyoxins has been cloned and sequenced from Streptomyces cacaoi and tens of polyoxin analogs have been identified already. RESULTS: The polyoxin biosynthetic gene...

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Detalles Bibliográficos
Autores principales: Li, Jine, Li, Lei, Feng, Chi, Chen, Yihua, Tan, Huarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520715/
https://www.ncbi.nlm.nih.gov/pubmed/23043373
http://dx.doi.org/10.1186/1475-2859-11-135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520715/
https://www.ncbi.nlm.nih.gov/pubmed/23043373
http://dx.doi.org/10.1186/1475-2859-11-135

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