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Quinine localizes to a non-acidic compartment within the food vacuole of the malaria parasite Plasmodium falciparum

BACKGROUND: The naturally fluorescent compound quinine has long been used to treat malaria infections. Although some evidence suggests that quinine acts in the parasite food vacuole, the mechanism of action of quinine has not yet been resolved. The Plasmodium falciparum multidrug resistance (pfmdr1)...

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Detalles Bibliográficos
Autores principales: Bohórquez, Elaine B, Chua, Michael, Meshnick, Steven R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520729/
https://www.ncbi.nlm.nih.gov/pubmed/23088166
http://dx.doi.org/10.1186/1475-2875-11-350