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Quinine localizes to a non-acidic compartment within the food vacuole of the malaria parasite Plasmodium falciparum
BACKGROUND: The naturally fluorescent compound quinine has long been used to treat malaria infections. Although some evidence suggests that quinine acts in the parasite food vacuole, the mechanism of action of quinine has not yet been resolved. The Plasmodium falciparum multidrug resistance (pfmdr1)...
Autores principales: | Bohórquez, Elaine B, Chua, Michael, Meshnick, Steven R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520729/ https://www.ncbi.nlm.nih.gov/pubmed/23088166 http://dx.doi.org/10.1186/1475-2875-11-350 |
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