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Algorithm development for corticosteroid management in systemic juvenile idiopathic arthritis trial using consensus methodology

BACKGROUND: The management of background corticosteroid therapy in rheumatology clinical trials poses a major challenge. We describe the consensus methodology used to design an algorithm to standardize changes in corticosteroid dosing during the Randomized Placebo Phase Study of Rilonacept in System...

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Detalles Bibliográficos
Autores principales: Ilowite, Norman T, Sandborg, Christy I, Feldman, Brian M, Grom, Alexi, Schanberg, Laura E, Giannini, Edward H, Wallace, Carol A, Schneider, Rayfel, Kenney, Kathleen, Gottlieb, Beth, Hashkes, Philip J, Imundo, Lisa, Kimura, Yukiko, Lang, Bianca, Miller, Michael, Milojevic, Diana, O’Neil, Kathleen M, Punaro, Marilynn, Ruth, Natasha, Singer, Nora G, Vehe, Richard K, Verbsky, James, Woodward, Amy, Zemel, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520770/
https://www.ncbi.nlm.nih.gov/pubmed/22931206
http://dx.doi.org/10.1186/1546-0096-10-31