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Schwann cell myelination requires Dynein function

BACKGROUND: Interaction of Schwann cells with axons triggers signal transduction that drives expression of Pou3f1 and Egr2 transcription factors, which in turn promote myelination. Signal transduction appears to be mediated, at least in part, by cyclic adenosine monophosphate (cAMP) because elevatio...

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Detalles Bibliográficos
Autores principales: Langworthy, Melissa M, Appel, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520773/
https://www.ncbi.nlm.nih.gov/pubmed/23167977
http://dx.doi.org/10.1186/1749-8104-7-37