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Notch Signaling Change in Pulmonary Vascular Remodeling in Rats with Pulmonary Hypertension and Its Implication for Therapeutic Intervention

Pulmonary hypertension (PH) is a fatal disease that lacks an effective therapy. Notch signaling pathway plays a crucial role in the angiogenesis and vascular remodeling. However, its roles in vascular remodeling in PH have not been well studied. In the current study, using hypoxia-induced PH model i...

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Detalles Bibliográficos
Autores principales: Qiao, Lina, Xie, Liang, Shi, Kun, Zhou, Tongfu, Hua, Yimin, Liu, Hanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520790/
https://www.ncbi.nlm.nih.gov/pubmed/23251561
http://dx.doi.org/10.1371/journal.pone.0051514