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Chemical Biology Drug Sensitivity Screen Identifies Sunitinib as Synergistic Agent with Disulfiram in Prostate Cancer Cells

BACKGROUND: Current treatment options for castration- and treatment-resistant prostate cancer are limited and novel approaches are desperately needed. Our recent results from a systematic chemical biology sensitivity screen covering most known drugs and drug-like molecules indicated that aldehyde de...

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Detalles Bibliográficos
Autores principales: Ketola, Kirsi, Kallioniemi, Olli, Iljin, Kristiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520796/
https://www.ncbi.nlm.nih.gov/pubmed/23251544
http://dx.doi.org/10.1371/journal.pone.0051470