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The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall Integrity

Cryptococcus neoformans survives host temperature and regulates cell wall integrity via a calcium-dependent phosphatase, calcineurin. However, downstream effectors of C. neoformans calcineurin are largely unknown. In S. cerevisiae and other fungal species, a calcineurin-dependent transcription facto...

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Detalles Bibliográficos
Autores principales: Lev, Sophie, Desmarini, Desmarini, Chayakulkeeree, Methee, Sorrell, Tania C., Djordjevic, Julianne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520850/
https://www.ncbi.nlm.nih.gov/pubmed/23251520
http://dx.doi.org/10.1371/journal.pone.0051403