Antitussive effects of the peripherally restricted GABA(B) receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABA(B) receptor-selective agonists

BACKGROUND: Gastroesophageal reflux disease (GERD) is a common cause of chronic cough. Both acid and nonacid reflux is thought to play a role in the initiation of coughing and cough hypersensitivity. The GABA(B) receptor agonist lesogaberan was developed as a peripherally restricted anti-reflux ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Canning, Brendan J, Mori, Nanako, Lehmann, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520872/
https://www.ncbi.nlm.nih.gov/pubmed/23025757
http://dx.doi.org/10.1186/1745-9974-8-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520872/
https://www.ncbi.nlm.nih.gov/pubmed/23025757
http://dx.doi.org/10.1186/1745-9974-8-7

Ejemplares similares