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Antitussive effects of the peripherally restricted GABA(B) receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABA(B) receptor-selective agonists

BACKGROUND: Gastroesophageal reflux disease (GERD) is a common cause of chronic cough. Both acid and nonacid reflux is thought to play a role in the initiation of coughing and cough hypersensitivity. The GABA(B) receptor agonist lesogaberan was developed as a peripherally restricted anti-reflux ther...

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Detalles Bibliográficos
Autores principales:	Canning, Brendan J, Mori, Nanako, Lehmann, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520872/ https://www.ncbi.nlm.nih.gov/pubmed/23025757 http://dx.doi.org/10.1186/1745-9974-8-7

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