Cargando…

Nitric oxide and histone deacetylases modulate cocaine-induced mu-opioid receptor levels in PC12 cells

BACKGROUND: Cocaine exposure has been reported to alter central μ-opioid receptor (MOR) expression in vivo. The present study employed an in vitro cellular model to explore possible mechanisms that may be involved in this action of cocaine. METHODS: To assess the effects of cocaine on MOR levels, tw...

Descripción completa

Detalles Bibliográficos
Autores principales: Winick-Ng, Warren, Leri, Francesco, Kalisch, Bettina E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520874/
https://www.ncbi.nlm.nih.gov/pubmed/23079001
http://dx.doi.org/10.1186/2050-6511-13-11