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Nitric oxide and histone deacetylases modulate cocaine-induced mu-opioid receptor levels in PC12 cells
BACKGROUND: Cocaine exposure has been reported to alter central μ-opioid receptor (MOR) expression in vivo. The present study employed an in vitro cellular model to explore possible mechanisms that may be involved in this action of cocaine. METHODS: To assess the effects of cocaine on MOR levels, tw...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520874/ https://www.ncbi.nlm.nih.gov/pubmed/23079001 http://dx.doi.org/10.1186/2050-6511-13-11 |