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Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A(2) from Bothrops pirajai venom

BACKGROUND: Harpalycin 2 (HP-2) is an isoflavone isolated from the leaves of Harpalyce brasiliana Benth., a snakeroot found in northeast region of Brazil and used in folk medicine to treat snakebite. Its leaves are said to be anti-inflammatory. Secretory phospholipases A(2) are important toxins foun...

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Detalles Bibliográficos
Autores principales: Ximenes, Rafael M, Alves, Renata S, Pereira, Ticiana P, Araújo, Renata M, Silveira, Edilberto R, Rabello, Marcelo M, Hernandes, Marcelo Z, Soares, Veronica C G, Bristot, Daniel, Pires, Camila L, Toyama, Daniela O, Gaeta, Henrique H, Monteiro, Helena S A, Toyama, Marcos H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520877/
https://www.ncbi.nlm.nih.gov/pubmed/22925825
http://dx.doi.org/10.1186/1472-6882-12-139