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Autoregulation of Sec7 Arf-GEF activity and localization by positive feedback

Members of the highly conserved Arf family of small GTPases serve as master regulators of vesicular transport. In yeast, Arf1 acts at the Golgi and trans-Golgi network (TGN) to recruit vesicular coat proteins and other effectors for both anterograde and retrograde transport. Arf1 is activated at the...

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Detalles Bibliográficos
Autores principales: Richardson, Brian C., Fromme, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520889/
https://www.ncbi.nlm.nih.gov/pubmed/22996016
http://dx.doi.org/10.4161/sgtp.21828