Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b

The main objective of this study was to examine effects of cocaine on HIV-1 replication in primary CD4+ T cells. Cocaine a commonly used drug among HIV-1 positive individuals serves as a cofactor for HIV-1 infection and progression to acquired immunodeficiency syndrome (AIDS). Accumulating evidence...

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Detalles Bibliográficos
Autores principales: Mantri, Chinmay K., Pandhare Dash, Jui, Mantri, Jyoti Velamarti, Dash, Chandravanu C. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520918/
https://www.ncbi.nlm.nih.gov/pubmed/23251514
http://dx.doi.org/10.1371/journal.pone.0051387