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Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease

BACKGROUND: Recent studies showed that polymorphisms in the Fat and Obesity-Associated (FTO) gene have robust effects on obesity, obesity-related traits and endophenotypes associated with Alzheimer's disease (AD). METHODS: We used 1,877 Caucasian cases and controls from the NIA-LOAD study and 1...

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Detalles Bibliográficos
Autores principales: Reitz, Christiane, Tosto, Giuseppe, Mayeux, Richard, Luchsinger, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520931/
https://www.ncbi.nlm.nih.gov/pubmed/23251365
http://dx.doi.org/10.1371/journal.pone.0050354