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Differential Dynamic Engagement within 24 SH3 Domain: Peptide Complexes Revealed by Co-Linear Chemical Shift Perturbation Analysis

There is increasing evidence for the functional importance of multiple dynamically populated states within single proteins. However, peptide binding by protein-protein interaction domains, such as the SH3 domain, has generally been considered to involve the full engagement of peptide to the binding...

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Detalles Bibliográficos
Autores principales: Stollar, Elliott J., Lin, Hong, Davidson, Alan R., Forman-Kay, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520974/
https://www.ncbi.nlm.nih.gov/pubmed/23251481
http://dx.doi.org/10.1371/journal.pone.0051282