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Diabetes-Induced Hepatic Pathogenic Damage, Inflammation, Oxidative Stress, and Insulin Resistance Was Exacerbated in Zinc Deficient Mouse Model

OBJECTIVES: Zinc (Zn) deficiency often occurs in the patients with diabetes. Effects of Zn deficiency on diabetes-induced hepatic injury were investigated. METHODS: Type 1 diabetes was induced in FVB mice with multiple low-dose streptozotocin. Hyperglycemic and age-matched control mice were treated...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Lu, Xuemian, Tan, Yi, Li, Bing, Miao, Xiao, Jin, Litai, Shi, Xue, Zhang, Xiang, Miao, Lining, Li, Xiaokun, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520990/
https://www.ncbi.nlm.nih.gov/pubmed/23251339
http://dx.doi.org/10.1371/journal.pone.0049257