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Natural selection drives rapid evolution of mouse embryonic heart enhancers

BACKGROUND: Mouse E11.5 embryonic heart enhancers were found to exhibit exceptionally weak sequence conservation during vertebrate evolution compared to enhancers of other developing organs. However, it is unknown whether this phenomenon is due to elevated mutation rates, or is a consequence of natu...

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Detalles Bibliográficos
Autores principales: Liao, Ben-Yang, Weng, Meng-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521173/
https://www.ncbi.nlm.nih.gov/pubmed/23281795
http://dx.doi.org/10.1186/1752-0509-6-S2-S1