A semi-supervised boosting SVM for predicting hot spots at protein-protein Interfaces

BACKGROUND: Hot spots are residues contributing the most of binding free energy yet accounting for a small portion of a protein interface. Experimental approaches to identify hot spots such as alanine scanning mutagenesis are expensive and time-consuming, while computational methods are emerging as...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Bin, Wei, Xiaoming, Deng, Lei, Guan, Jihong, Zhou, Shuigeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521187/
https://www.ncbi.nlm.nih.gov/pubmed/23282146
http://dx.doi.org/10.1186/1752-0509-6-S2-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521187/
https://www.ncbi.nlm.nih.gov/pubmed/23282146
http://dx.doi.org/10.1186/1752-0509-6-S2-S6

Ejemplares similares